A Quality framework for remote antenatal care: qualitative study with women, healthcare professionals and system-level stakeholders

Lisa Hinton, Francesca H Dakin, Karolina Kuberska, Nicola Boydell, Janet Willars, Tim Draycott, Cathy Winter, Richard J McManus, Lucy C Chappell, Sanhita Chakrabarti, Elizabeth Howland, Jenny George, Brandi Leach, Mary Dixon-Woods

Published in the BMJ May 2022

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Effect of Self-monitoring of Blood Pressure on Diagnosis of Hypertension During Higher-Risk Pregnancy – The BUMP 1 Randomized Clinical Trial

Katherine L. Tucker, Sam Mort, Ly-Mee Yu, Helen Campbell, Oliver Rivero-Arias, Hannah M. Wilson, Julie Allen, Rebecca Band, Alison Chisholm, Carole Crawford, Greig Dougall, Lazarina Engonidou, Marloes Franssen, Marcus Green, Sheila Greenfield, Lisa Hinton, James Hodgkinson, Layla Lavallee, Paul Leeson, Christine McCourt, Lucy Mackillop, Jane Sandall, Mauro Santos, Lionel Tarassenko, Carmelo Velardo, Lucy Yardley, Lucy C. Chappell, Richard J. McManus

Published in Journal of the American Medical Association May 2022

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Effect of Self-monitoring of Blood Pressure on Blood Pressure Control in Pregnant Individuals With Chronic or Gestational Hypertension – The BUMP 2 Randomized Clinical Trial

Lucy C. Chappell, Katherine L. Tucker, Ushma Galal, Ly-Mee Yu, Helen Campbell, Oliver Rivero-Arias, Julie Allen, Rebecca Band, Alison Chisholm, Carole Crawford, MSc; Greig Dougall, Lazarina Engonidou, Marloes Franssen, Marcus Green, Sheila Greenfield, Lisa Hinton, James Hodgkinson, Layla Lavallee, Paul Leeson, Christine McCourt, Lucy Mackillop, Jane Sandall, Mauro Santos, Lionel Tarassenko, Carmelo Velardo, Hannah Wilson, Lucy Yardley, PhD; Richard J. McManus

Published in Journal of the American Medical Association May 2022

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Planned delivery or expectant management in pre-eclampsia: an individual participant data meta-analysis

Alice Beardmore-Gray, Paul T. Seed, Jessica Fleminger, Eva Zwertbroek, Thomas Bernardes, Ben W.Mol, Cheryl Battersby, Corine Koopmans, Kim Broekhuijsen, Kim Boers, Michelle Y.Owens, JimThornton, Marcus Green, Andrew H.Shennan, Henk Groen, Lucy C.Chappell

Published in American Journal of Obstetrics and Gynaecology, 26th April 2022

https://doi.org/10.1016/j.ajog.2022.04.034

Two‐year follow‐up of infant and maternal outcomes after planned early delivery or expectant management for late preterm pre‐eclampsia (PHOENIX): a randomised controlled trial

Alice Beardmore-Gray, Melanie Greenland, Louise Linsell, Edmund Juszczak, Pollyanna Hardy, Anna Placzek, Rachael Hunter, Jenie Sparkes, Marcus Green, Andrew H Shennan, Neil Marlow, Lucy C Chappell

Published in BJOG An International Journal of Obstetrics & Gynaecology April 2022

DOI:10.1111/1471-0528.17167

Postnatal health and care following hypertensive disorders in pregnancy: a prospective cohort study (BPiPP study)

Danielle Ashworth, Liza Bowen, Paul T. Seed, Sophie P. Maule, Marcus Edward Green, Debra E Bick, Lucy C. Chappell

Published in BMC Pregnancy and Childbirth 22(1) April 2022 DOI Read the paper

Paracetamol use in pregnancy — neglecting context promotes misinterpretation

Joseph O’Sullivan, Alexandra E. Cairns, Elena Plesca, Rebecca S. Black, Charlotte Frise, Manu Vatish and Ana Sofia Cerdeira

Published in Nature Reviews Endocrinology March 2022

PMID: 35277662DOI: Read the paper View PDF

Which antihypertensive treatment is better for mild to moderate hypertension in pregnancy?

Danielle Ashworth,  Cheryl Battersby, Marcus Green,  Pollyanna Hardy,  Richard J McManus, Catherine Cluver, Lucy C Chappell, 

Published in BMJ 2022; 376 18th January 2022

Read the paper BMJ 2022;376:e066333

Factors influencing perinatal outcomes in women with preterm pre-eclampsia: A secondary analysis of the PHOENIX trial

Jessica Fleminger, Kate Duhig, Paul T Seed, Peter Brocklehurst, Marcus Green, Edmund Juszczak, Neil Marlow, Andrew H Shennan, Lucy C Chappell

Published in Pregnancy Hypertension, 26 (1) December 2021

DOI:10.1016/j.preghy.2021.10.002

Planned delivery to improve postpartum cardiac function in women with preterm pre-eclampsia: the PHOEBE mechanisms of action study within the PHOENIX RCT

Fergus P McCarthy, Jamie O’Driscoll, Paul Seed, Anna Brockbank, Alice Cox, Carolyn Gill, Marcus Green, Mike Marber, Lucilla Poston, Anna Placzek, Andrew Shennan, Jenie Sparkes, Paul Leeson, Basky Thilaganathan, Lucy C Chappell 

Published in Efficacy and Mechanism Evaluation September 21 2021

Read the paper DOI: 10.3310/eme08120

The impact of pre-eclampsia definitions on the identification of adverse outcome risk in hypertensive pregnancy – analyses from the CHIPS trial (Control of Hypertension in Pregnancy Study)

L A Magee , J Singer, T Lee , E Rey, E Asztalo , E Hutton  M Helewa , A G Logan, W Ganzevoort , R Welch , J G Thornton , M L Woo Kinshella , M Green , E Tsigas , P von Dadelszen 

Published in BJOG: An International Journal of Obstetrics and Gynaecology November 2020

Read the paper PMID: 33230924 DOI: 10.1111/1471-0528.16602

Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis.

Allotey J, Snell KI, Smuk M, Hooper R, Chan CL, Ahmed A, Chappell LC, von Dadelszen P, Dodds J, Green M, Kenny L, Khalil A, Khan KS, Mol BW, Myers J, Poston L, Thilaganathan B, Staff AC, Smith GC, Ganzevoort W, Laivuori H, Odibo AO, Ramírez JA, Kingdom J, Daskalakis G, Farrar D, Baschat AA, Seed PT, Prefumo F, da Silva Costa F, Groen H, Audibert F, Masse J, Skråstad RB, Salvesen KÅ, Haavaldsen C, Nagata C, Rumbold AR, Heinonen S, Askie LM, Smits LJ, Vinter CA, Magnus PM, Eero K, Villa PM, Jenum AK, Andersen LB, Norman JE, Ohkuchi A, Eskild A, Bhattacharya S, McAuliffe FM, Galindo A, Herraiz I, Carbillon L, Klipstein-Grobusch K, Yeo S, Teede HJ, Browne JL, Moons KG, Riley RD, Thangaratinam S.

Published in Health Technology Assessment. December 2020 24(72):1-252.

Read the paper PMID: 33336645; PMCID: PMC7780127.

PHOENIX Study Group. Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial

Chappell LC, Brocklehurst P, Green ME, Hunter R, Hardy P, Juszczak E, Linsell L, Chiocchia V, Greenland M, Placzek A, Townend J, Marlow N, Sandall J, Shennan A

Published in The Lancet. 2019 Sep 28; 394(10204):1181-1190.

 Read the paper PMID: 31472930; PMCID: PMC6892281.

Planned delivery or expectant management for late preterm pre-eclampsia: study protocol for a randomised controlled trial (PHOENIX trial).

Chappell LC, Green M, Marlow N, Sandall J, Hunter R, Robson S, Bowler U, Chiocchia V, Hardy P, Juszczak E, Linsell L, Placzek A, Brocklehurst P, Shennan A.

Published in Trials. 2019 Jan 28;20(1):85.

Read the paper PMID: 30691508; PMCID: PMC6350286.

Reducing maternal deaths from hypertensive disorders: learning from confidential inquiries.

Conti-Ramsden F, Knight M, Green M, Shennan AH, Chappell LC.

Published in the British Medical Journal (BMJ). 2019 Feb 5;364:l230.

Read the paper. PMID: 30723108.

Maternal deaths in the UK: pre-eclampsia deaths are avoidable

Shennan AH, Green M, Chappell LC. Published in The Lancet. 2017 Feb 11;389(10069):582-584.

Read the paper PMID: 28195043.

Aspirin should be targeted to those who need it

Green M, Shennan A.

Published in BJOG. 2020 Sep 5.

Read the paper. PMID: 32892486.

IPPIC Network. Prediction of pre-eclampsia: review of reviews.

Townsend R, Khalil A, Premakumar Y, Allotey J, Snell KIE, Chan C, Chappell LC, Hooper R, Green M, Mol BW, Thilaganathan B, Thangaratinam S;

Published in Ultrasound Obstet Gynecol. 2019 Jul;54(1):16-27.

 Read the paper  PMID: 30267475.

Why is the search for pre-eclampsia prevention so elusive?

Myers JE, Green M, Chappell LC.

Published in The BMJ. 2018 Sep 12;362:k3536.

 Read the paper PMID: 30209065.

IPPIC Collaborative Network. External validation, update and development of prediction models for pre-eclampsia using an Individual Participant Data (IPD) meta-analysis: The International Prediction of Pregnancy Complication Network (IPPIC pre-eclampsia)

Allotey J, Snell KIE, Chan C, Hooper R, Dodds J, Rogozinska E, Khan KS, Poston L, Kenny L, Myers J, Thilaganathan B, Chappell L, Mol BW, Von Dadelszen P, Ahmed A, Green M, Poon L, Khalil A, Moons KGM, Riley RD, Thangaratinam S

Published in Diagnostic and Prognostic Research. 2017 Oct 3;1:16.

Read the paper PMID: 31093545; PMCID: PMC6460674.

IPPIC Collaborative Network. External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis.

Snell KIE, Allotey J, Smuk M, Hooper R, Chan C, Ahmed A, Chappell LC, Von Dadelszen P, Green M, Kenny L, Khalil A, Khan KS, Mol BW, Myers J, Poston L, Thilaganathan B, Staff AC, Smith GCS, Ganzevoort W, Laivuori H, Odibo AO, Arenas Ramírez J, Kingdom J, Daskalakis G, Farrar D, Baschat AA, Seed PT, Prefumo F, da Silva Costa F, Groen H, Audibert F, Masse J, Skråstad RB, Salvesen KÅ, Haavaldsen C, Nagata C, Rumbold AR, Heinonen S, Askie LM, Smits LJM, Vinter CA, Magnus P, Eero K, Villa PM, Jenum AK, Andersen LB, Norman JE, Ohkuchi A, Eskild A, Bhattacharya S, McAuliffe FM, Galindo A, Herraiz I, Carbillon L, Klipstein-Grobusch K, Yeo SA, Browne JL, Moons KGM, Riley RD, Thangaratinam S

Published in BMC Medicine. 2020 Nov 2;18(1):302.

Read the paper PMID: 33131506; PMCID: PMC7604970.

Research priorities for pregnancy hypertension: a UK priority setting partnership with the James Lind Alliance.

Ho A, Webster L, Bowen L, Creighton F, Findlay S, Gale C, Green M, Gronlund T, Magee LA, McManus RJ, Mistry HD, Singleton G, Thornton J, Whybrow R, Chappell L.

Published in BMJ Open. 2020 Jul 14;10(7):e036347.

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Blood pressure monitoring in high-risk pregnancy to improve the detection and monitoring of hypertension (the BUMP 1 and 2 trials): protocol for two linked randomised controlled trials.

Dougall G, Franssen M, Tucker KL, Yu LM, Hinton L, Rivero-Arias O, Abel L, Allen J, Band RJ, Chisholm A, Crawford C, Green M, Greenfield S, Hodgkinson J, Leeson P, McCourt C, MacKillop L, Nickless A, Sandall J, Santos M, Tarassenko L, Velardo C, Wilson H, Yardley L, Chappell L, McManus RJ.

Published in BMJ Open. 2020 Jan 23;10(1):e034593.

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External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis. 

Snell, K.I.E., Allotey, J., Smuk, M. et al. 

Published in BMC Medicine 18, 302 (2020)

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Guidance for maternal medicine in the evolving coronavirus (COVID-19) pandemic

Published in RCOG 2020

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MBRRACE-UK The Confidential Enquiry into Maternal Deaths: Saving Lives, Improving Mothers’ Care

Annual report 2016, 2017, 2019, 2021 – Green, M Co-wrote lay summary

Read the report and lay summary