The impact of pre-eclampsia definitions on the identification of adverse outcome risk in hypertensive pregnancy – analyses from the CHIPS trial (Control of Hypertension in Pregnancy Study)

L A Magee , J Singer, T Lee , E Rey, E Asztalo , E Hutton  M Helewa , A G Logan, W Ganzevoort , R Welch , J G Thornton , M L Woo Kinshella , M Green , E Tsigas , P von Dadelszen 

Published in BJOG: An International Journal of Obstetrics and Gynaecology June 2021

Read the paper PMID: 33230924 DOI: 10.1111/1471-0528.16602

Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis.

Allotey J, Snell KI, Smuk M, Hooper R, Chan CL, Ahmed A, Chappell LC, von Dadelszen P, Dodds J, Green M, Kenny L, Khalil A, Khan KS, Mol BW, Myers J, Poston L, Thilaganathan B, Staff AC, Smith GC, Ganzevoort W, Laivuori H, Odibo AO, Ramírez JA, Kingdom J, Daskalakis G, Farrar D, Baschat AA, Seed PT, Prefumo F, da Silva Costa F, Groen H, Audibert F, Masse J, Skråstad RB, Salvesen KÅ, Haavaldsen C, Nagata C, Rumbold AR, Heinonen S, Askie LM, Smits LJ, Vinter CA, Magnus PM, Eero K, Villa PM, Jenum AK, Andersen LB, Norman JE, Ohkuchi A, Eskild A, Bhattacharya S, McAuliffe FM, Galindo A, Herraiz I, Carbillon L, Klipstein-Grobusch K, Yeo S, Teede HJ, Browne JL, Moons KG, Riley RD, Thangaratinam S.

Published in Health Technol Assess. December 2020 24(72):1-252.

 Read the paper. PMID: 33336645; PMCID: PMC7780127.

Planned Early Delivery or Expectant Management for Late Preterm Pre-eclampsia (PHOENIX): A Randomized Controlled Trial, on behalf of the PHOENIX Study Group

Chappell, L.C.; Brocklehurst, P.; Green, M.E.; Hunter, R.; Hardy, P.; Juszczak, E.; Linsell, L.; Chiocchia, V.; Greenland, M.; Placzek, A.; Townend, J.; Marlow, N.; Sandall, J.; Shennan, A.

Published in Obstetric Anesthesia Digest: September 2020 – Volume 40 – Issue 3 – p 136-137

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PHOENIX Study Group. Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial

Chappell LC, Brocklehurst P, Green ME, Hunter R, Hardy P, Juszczak E, Linsell L, Chiocchia V, Greenland M, Placzek A, Townend J, Marlow N, Sandall J, Shennan A

Published in The Lancet. 2019 Sep 28; 394(10204):1181-1190.

 Read the paper PMID: 31472930; PMCID: PMC6892281.

Planned delivery or expectant management for late preterm pre-eclampsia: study protocol for a randomised controlled trial (PHOENIX trial).

Chappell LC, Green M, Marlow N, Sandall J, Hunter R, Robson S, Bowler U, Chiocchia V, Hardy P, Juszczak E, Linsell L, Placzek A, Brocklehurst P, Shennan A.

Published in Trials. 2019 Jan 28;20(1):85.

Read the paper PMID: 30691508; PMCID: PMC6350286.

Reducing maternal deaths from hypertensive disorders: learning from confidential inquiries.

Conti-Ramsden F, Knight M, Green M, Shennan AH, Chappell LC.

Published in the British Medical Journal (BMJ). 2019 Feb 5;364:l230.

Read the paper. PMID: 30723108.

Maternal deaths in the UK: pre-eclampsia deaths are avoidable

Shennan AH, Green M, Chappell LC. Published in The Lancet. 2017 Feb 11;389(10069):582-584.

Read the paper PMID: 28195043.

Aspirin should be targeted to those who need it

Green M, Shennan A.

Published in BJOG. 2020 Sep 5.

Read the paper. PMID: 32892486.

IPPIC Network. Prediction of pre-eclampsia: review of reviews.

Townsend R, Khalil A, Premakumar Y, Allotey J, Snell KIE, Chan C, Chappell LC, Hooper R, Green M, Mol BW, Thilaganathan B, Thangaratinam S;

Published in Ultrasound Obstet Gynecol. 2019 Jul;54(1):16-27.

 Read the paper  PMID: 30267475.

Why is the search for pre-eclampsia prevention so elusive?

Myers JE, Green M, Chappell LC.

Published in The BMJ. 2018 Sep 12;362:k3536.

 Read the paper PMID: 30209065.

IPPIC Collaborative Network. External validation, update and development of prediction models for pre-eclampsia using an Individual Participant Data (IPD) meta-analysis: The International Prediction of Pregnancy Complication Network (IPPIC pre-eclampsia)

Allotey J, Snell KIE, Chan C, Hooper R, Dodds J, Rogozinska E, Khan KS, Poston L, Kenny L, Myers J, Thilaganathan B, Chappell L, Mol BW, Von Dadelszen P, Ahmed A, Green M, Poon L, Khalil A, Moons KGM, Riley RD, Thangaratinam S

Published in Diagn Progn Res. 2017 Oct 3;1:16.

Read the paper PMID: 31093545; PMCID: PMC6460674.

IPPIC Collaborative Network. External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis.

Snell KIE, Allotey J, Smuk M, Hooper R, Chan C, Ahmed A, Chappell LC, Von Dadelszen P, Green M, Kenny L, Khalil A, Khan KS, Mol BW, Myers J, Poston L, Thilaganathan B, Staff AC, Smith GCS, Ganzevoort W, Laivuori H, Odibo AO, Arenas Ramírez J, Kingdom J, Daskalakis G, Farrar D, Baschat AA, Seed PT, Prefumo F, da Silva Costa F, Groen H, Audibert F, Masse J, Skråstad RB, Salvesen KÅ, Haavaldsen C, Nagata C, Rumbold AR, Heinonen S, Askie LM, Smits LJM, Vinter CA, Magnus P, Eero K, Villa PM, Jenum AK, Andersen LB, Norman JE, Ohkuchi A, Eskild A, Bhattacharya S, McAuliffe FM, Galindo A, Herraiz I, Carbillon L, Klipstein-Grobusch K, Yeo SA, Browne JL, Moons KGM, Riley RD, Thangaratinam S

Published in The BMC Med. 2020 Nov 2;18(1):302.

Read the paper PMID: 33131506; PMCID: PMC7604970.

Research priorities for pregnancy hypertension: a UK priority setting partnership with the James Lind Alliance.

Ho A, Webster L, Bowen L, Creighton F, Findlay S, Gale C, Green M, Gronlund T, Magee LA, McManus RJ, Mistry HD, Singleton G, Thornton J, Whybrow R, Chappell L.

Published in BMJ Open. 2020 Jul 14;10(7):e036347.

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Blood pressure monitoring in high-risk pregnancy to improve the detection and monitoring of hypertension (the BUMP 1 and 2 trials): protocol for two linked randomised controlled trials.

Dougall G, Franssen M, Tucker KL, Yu LM, Hinton L, Rivero-Arias O, Abel L, Allen J, Band RJ, Chisholm A, Crawford C, Green M, Greenfield S, Hodgkinson J, Leeson P, McCourt C, MacKillop L, Nickless A, Sandall J, Santos M, Tarassenko L, Velardo C, Wilson H, Yardley L, Chappell L, McManus RJ.

Published in BMJ Open. 2020 Jan 23;10(1):e034593.

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External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis. 

Snell, K.I.E., Allotey, J., Smuk, M. et al. 

Published in BMC Med 18, 302 (2020)

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The impact of pre‐eclampsia definitions on the identification of adverse outcome risk in hypertensive pregnancy ‐ analyses from the CHIPS trial (Control of Hypertension in Pregnancy Study).

Magee L.A, Singer J, Lee T, Rey E, Asztalos, E, Hutton E, Helewa M, Loga, A.G, Ganzevoort W, Welch R, Thornton J, Woo‐Kinshella M.L, Green M, Tsigas, E, von Dadelszen P.

Published in BJOG November 2020. 

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Blood pressure monitoring in high-risk pregnancy to improve the detection and monitoring of hypertension (the BUMP 1 and 2 trials): protocol for two linked randomised controlled trials.

Dougall G, Franssen M, Tucker KL, Yu LM, Hinton L, Rivero-Arias O, Abel L, Allen J, Band RJ, Chisholm A, Crawford C, Green M, Greenfield S, Hodgkinson J, Leeson P, McCourt C, MacKillop L, Nickless A, Sandall J, Santos M, Tarassenko L, Velardo C, Wilson H, Yardley L, Chappell L, McManus RJ.

Published in BMJ Open. 2020 Jan 23;10(1):e034593.

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IPPIC Collaborative Network; External validation, update and development of prediction models for pre-eclampsia using an Individual Participant Data (IPD) meta-analysis: The International Prediction of Pregnancy Complication Network (IPPIC pre-eclampsia) protocol

John Allotey, Kym I. E. Snell, Claire Chan, Richard Hooper, Julie Dodds, Ewelina Rogozinska, Khalid S. Khan, Lucilla Poston, Louise Kenny, Jenny Myers, Basky Thilaganathan, Lucy Chappell, Ben W. Mol, Peter Von Dadelszen, Asif Ahmed, Marcus Green, Liona Poon, Asma Khalil, Karel G. M. Moons, Richard D. Riley, Shakila Thangaratinam

Published in Diagn Progn Res 1, 16 (2017).

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Research priorities for pregnancy hypertension: a UK priority setting partnership with the James Lind Alliance

Ho A, Webster L, Bowen L, Creighton F, Findlay S, Gale C, Green M, Gronlund T, Magee LA, McManus RJ, Mistry HD, Singleton G, Thornton J, Whybrow R, Chappell L.

Published in the BMJ Open 2020;10:e036347.

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Planned Early Delivery or Expectant Management for Late Preterm Pre-eclampsia (PHOENIX): A Randomized Controlled Trial

Chappell, Lucy C.; Brocklehurst, Peter; Green, Marcus E.; Hunter, Rachael; Hardy, Pollyanna; Juszczak, Edmund; Linsell, Louise; Chiocchia, Virginia; Greenland, Melanie; Placzek, Anna; Townend, John; Marlow, Neil; Sandall, Jane; Shennan, Andrew

Published in Obstetrical & Gynecological Survey: February 2020 – Volume 75 – Issue 2 – p 83-84

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Guidance for maternal medicine in the evolving coronavirus (COVID-19) pandemic

Published in RCOG 2020

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MBRRACE-UK The Confidential Enquiry into Maternal Deaths: Saving Lives, Improving Mothers’ Care

Annual report 2016, 2017, 2019, 2021 – Green, M Co-wrote lay summary

Read the report and lay summary